Palo Santo is a venture capital firm. Based in Chicago & NYC, United States. Among the 9 companies in the known portfolio are Beacon Biosignals, Fluence, Gilgamesh Pharmaceuticals, Journey Clinical, Sensorium Therapeutics and Xylo Bio.
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Investment focus
- Sector
- EducationHealthcare
Who to pitch at Palo Santo
Palo Santo portfolio companies (9)
- Beacon Biosignals
- Fluence
- Gilgamesh Pharmaceuticals
- Journey Clinical
- Sensorium Therapeutics
- Xylo Bio
- Kanna Health
- Reunion Neuroscience
- Syndeio Biosciences
Co-investors
Funds that share portfolio companies with Palo Santo.
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About Palo Santo
The firm's listing covers sectors Education and Healthcare, and focus areas Biotech, Digital Health, Drug Discovery and Life Science; known deals cluster at Seed, Series A and Series B.
The contacts to approach at Palo Santo are Tony Eisenberg (Partner and Co-Founder) and Daniel Goldberg (Co-Founder & Partner).
Across the known portfolio, 20 co-investors appear alongside Palo Santo, including Neo Kuma Ventures, re.Mind and Iter Investments.
Frequently asked questions
What is Palo Santo?
Palo Santo is a venture capital firm based in Chicago & NYC, United States, with a known portfolio of 9 companies. The portfolio comes from public investment records rather than from the firm, so deals that never surfaced publicly are not in it.
What does Palo Santo invest in?
Listed sectors include Education and Healthcare; listed focus areas include Biotech, Digital Health, Drug Discovery and Life Science. Those tags come from the portfolio attached to the firm, so they describe what has been backed rather than a stated mandate for what comes next.
What stage does Palo Santo invest at?
The known deals of Palo Santo include Seed, Series A and Series B rounds. Check that against your own round before reaching out: stage mismatch is the most common reason a well matched sector still goes nowhere.
Who should I pitch at Palo Santo?
Both people on file at Palo Santo are listed as contacts for the firm, each with their own profile page.
How do I contact Palo Santo?
Any email address on file for the firm is masked on this page and readable inside RaiseHunt after you create an account. The 2 people attached to the firm have their own pages, each showing whether an address is on file for them.
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Data: RaiseHunt investor dataset · Snapshot 5 September 2026 · How this data is built · Report a correction or request removal