Investor profile
Matthew De Silva
Angel, Operator angel, Syndicate / Angel group & Venture Partner at Builders VC
An angel investor and operator angel based in Chicago, Illinois, United States, Matthew De Silva has 3 known investments: Enveda Biosciences, Arpeggio Bio and Eigen Therapeutics.
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Investment focus
- Stage
- Seed
- Sector
- AIHealthcare
Contacts
Matthew De Silva portfolio companies (3)
- Enveda Biosciences
- Arpeggio Bio
- Eigen Therapeutics
Affiliated funds' portfolios
Venture Partner at Builders VC, whose known portfolio counts 16 companies
- Cambio
- Knapsack
- Augment Markets
- Future Fields
- Pie Systems
- UbiQD
- Brilliant Harvest
- CourseKey
- The Biological Computing
- Puna Bio
- AuX Labs
- 280 Earth
- and 4 more
Investor Profile
The known portfolio sits in sectors AI and Healthcare, and focus areas Biotech, Clinical Trials, Computational Biology and Data Science.
Stage-wise, the known deals cluster around Seed rounds.
The portfolio and focus above give founders context on whether Matthew De Silva matches their raise.
Colleagues at Builders VC
Amit Mehta
General Partner
San Antonio, United States
Daniel Lubetzky
Founder
New York, United States
Alex Kruglov
Founding Partner
New York City, United States
Jim Kim
Founding Partner
San Francisco, United States
Mark Blackwell
General Partner & Chief Operating Officer
Calgary, Canada
Johnny LaLonde
Venture Partner
San Francisco, United States
Julia Bramer
Investor
Amsterdam, Netherlands
Steve Dell'Orto
Venture Partner
San Francisco, United States
Mark H Goldstein
Venture Builder
Belvedere, United States
Jocelyn D.
General Partner
San Francisco, United States
Amy Falvo
Chief Executive Officer
San Francisco, United States
Paul Verhesen
Venture Partner
Canada
Angelica Maestas
Investor
Albuquerque, United States
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Frequently asked questions
Who is Matthew De Silva?
Matthew De Silva is an angel investor and operator angel based in Chicago, Illinois, United States with 3 known investments on file, among them Enveda Biosciences, Arpeggio Bio and Eigen Therapeutics. The sections above list the sectors, stages and firms attached to that record.
What does Matthew De Silva invest in?
Listed sectors include AI and Healthcare; listed focus areas include Biotech, Clinical Trials, Computational Biology and Data Science. Those tags come from the companies attached to this profile, so they read as a record of what has been backed rather than a stated preference for what comes next.
What stage does Matthew De Silva invest at?
The known deals of Matthew De Silva include Seed rounds. Stage is the strongest single filter when you build a target list: an investor with no record at your stage rarely starts with you.
Which firm is Matthew De Silva listed at?
Matthew De Silva is listed as Venture Partner at Builders VC. 13 other people in the database share a firm with Matthew De Silva.
How do I contact Matthew De Silva?
An email address, a phone number and a LinkedIn page are on file for Matthew De Silva. The address stays masked on this page and is readable inside RaiseHunt after you create an account.
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Data: RaiseHunt investor dataset · Snapshot 5 September 2026 · How this data is built · Report a correction or request removal